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Kurzbeschreibung:The aim of this thesis is to establish a new method for the measurement of molecular forces by applying tension sensors based on FRET to pancreatic cancer organoids. Confocal microscopy and digital imaging processing and analysis will be employed to understand how mechanical forces lead to structure formation processes in organmorphogenesis. Your Profile:• Surpassing grades in your master’s program in biology,  … Weiterlesen

Short description:The aim of this thesis is to establish a new method for the measurement of molecular forces by applying tension sensors based on FRET to pancreatic cancer organoids. Confocal microscopy and digital imaging processing and analysis will be employed to understand how mechanical forces lead to structure formation processes in organmorphogenesis. Your Profile:• Surpassing grades in your bachelor’s program in  … Weiterlesen

Kurzbeschreibung: Entwicklung eines neuen Setups für die Potentialkontrollierte Membranchromatographie.Aufgaben: Entwicklung eines Membranmoduls, Simulation der Strömungseigenschaften, Inbetriebnahme an einer präparativen ChromatographieanlageAnforderungen: Kreativität und handwerkliches Geschick, Spaß an angewandter Forschung, Von Vorteil: Erste Kenntnisse in CAD und Comsol Beschreibung: Ziel dieses Forschungsprojektes ist die Entwicklung eines neuartigen Chromatographieprozesses unter Einsatz von leitfähigen Membranen. Diese können in ihrer  … Weiterlesen

Short description:At the Laboratory of Chemical Process Engineering, a new project about carbon capture and storage has recently started. The overall aim of the project is to reduce the amount of carbon in the atmosphere by developing a suitable long-term carbon storage in Bavaria. There are various carbon sources, such as CO2 from air, minerals,  … Weiterlesen

Kurzbeschreibung: The Oncology Department of the Novartis Institute for Biomedical Research in Basel, Switzerland is currently looking for interns in the field of molecular and cellular biology. Positions are available for 6 months to work on different aspects of cancer biology.You will be involved in cutting-edge research using the latest technologies in genetic manipulation, molecular  … Weiterlesen

Short description: 1. Targeting RORγt/DHODH signaling in islet autoimmunity and Type 1 Diabetes 2. The role of T cell-specific IL6Rα signaling in maintaining tissue immune homeostasis Description: 1. We investigate the influence of RORγt/DHODH inhibition on Tregs and different T cell subsets in islet autoimmunity and T1D. Using various in vitro approaches and loss-of-function or T1D  … Weiterlesen

Dymium is an early-stage MedTech startup based in Munich. Our team has developed and patented a new surgical method for the residue-free, minimal-invasive removal of kidney stone fragments using magnetism. This has the potential to save thousands of patients from follow-up surgeries every year. We are looking for a student (m/f/d) to help us with  … Weiterlesen

Short description: Quantum sensors in diamond are a promising platform for the detection of DNA sequences. Description: Recent experiments have shown that defects in diamond, in particular nitrogen-vacancy (NV) centers, can be used as quantum sensors for detecting nuclear magnetic resonance (NMR) signals from tiny volumes down to a single molecule. Our group applies this  … Weiterlesen

Description: Brenda Schulman laboratory, Molecular Machines and Signaling Department, Max Planck Institute of Biochemistry Background:Protein modification by the small protein ubiquitin regulates nearly all aspects of eukaryotic biology.  A particular type of modification, where proteins are decorated by “chains” of ubiquitin proteins covalently linked to each other, direct proteins for degradation by the proteasome.  Defects  … Weiterlesen

Short: The overarching aim of the Mougel group research at ETH Zürich is to provide energy efficient strategies for the (electro)chemical transformation of small molecules such as nitrogen or carbon dioxide to high value-added products. Molecular catalysts allow for a high tunability of reaction active sites. We hereby take our inspiration from Nature, by aiming  … Weiterlesen

At TUM Campus Straubing for Biotechnology and Sustainability, the Chair of Chemistry of Biogenic Resources (Prof. Volker Sieber) deals with the development of chemical and biotechnological processes for the conversion of biomass to base chemicals, biofuels, and fine chemicals. For this work, the focus of research is on protein biochemistry (enzymeengineering), molecular biology (cloning, mutagenesis),  … Weiterlesen

Kurzbeschreibung: Do you want use femtosecond laser-spectroscopy to study photosynthetic energy-conversion? Beschreibung: All forms of higher life on earth rely directly or indirectly on photosynthesis – the biological conversion of light into chemical energy. Substantial attention is being paid to these crucial processes, not only in terms of fundamental principles of nature, but also as  … Weiterlesen

For students of chemical engineering or chemistry with focus technical chemistry (Professur für Anorganische Chemie, Prof. Dr. K. Köhler & Max Hiller) Motivation and problem definition: Hydrogenations belong to the most relevant reactions in industrial practice. Structure-activity relationships and mechanistic investigations are important for catalyst optimization. For that reason, an existing and well-working fixed bed  … Weiterlesen