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Praktika Sonstige Stellenangebote Stellenangebote

Internship position at Novartis Institute for Biomedical Research (NIBR)

Description:
The Oncology Department of the Novartis Institute for Biomedical Research in Basel, Switzerland, is recurrently looking for an intern in the field of molecular and cellular biology. The position is available for 6 months starting from April / May 2022 to work on different aspects of cancer biology.
You will be involved in cutting-edge research using the latest technologies in genetic manipulation, genetic screens and (epi-) genome profiling.
You will join an enthusiastic team working on transcriptional regulation to dissect the molecular functions of a number of candidate oncogenes and in diverse cancer settings.

Your tasks will be:

  • Design, execute and/or analyze experimental work with the supervision of
    different team members
  • Contribute to lab / team organization and projects development
  • Formulate and test additional hypothesis based on a large amount of internal data in different fields
  • Provide accurate raw data documentation, evaluation and results interpretation

    Requirements:
  • M.Sc. degree in Molecular Biology or Cancer biology (and related) recently
    obtained.
  • Experience with mammalian cell culture, basic cell biology techniques and
    molecular biology is required.
  • Knowledge in basic bioinformatics (to handle large datasets) or protein
    biochemistry/structure is advantageous but not required.
  • Interest / knowledge in the epigenetics/transcription field are advantageous but not required.
  • Good organizational skills with respect to planning, tracking and adherence to timelines
  • Good communication, presentation and scientific writing skills
  • Fluency in English is mandatory (oral & written)

Kontakt: Giorgio Galli, giorgio.galli[ät]novartis.com

Kategorien
Abschlussarbeiten Praktika Stellenangebote

BA / SA / MA: Potentialkontrollierte Membranchromatographie – Setup Design

Kurzbeschreibung:
Entwicklung eines neuen Setups für die Potentialkontrollierte Membranchromatographie.
Aufgaben: Entwicklung eines Membranmoduls, Simulation der Strömungseigenschaften, Inbetriebnahme an einer präparativen Chromatographieanlage
Anforderungen: Kreativität und handwerkliches Geschick, Spaß an angewandter Forschung, Von Vorteil: Erste Kenntnisse in CAD und Comsol

Beschreibung:
Ziel dieses Forschungsprojektes ist die Entwicklung eines neuartigen Chromatographieprozesses unter Einsatz von leitfähigen Membranen. Diese können in ihrer Ladung und folglich ihrem Bindecharakter beeinflusst werden und ermöglichen somit eine potentialkontrollierte Elution des Zielmoleküls. Dadurch kann die Biomolekülaufreinigung nicht nur effizienter und kostengünstiger sondern auch nachhaltiger erfolgen.
In dieser Abschlussarbeit soll ein neues Membranmodul für den Einsatz an einer präparativen Chromatographieanlage mittels CAD entworfen werden. Die Strömungseigenschaften des Moduls spielen hierbei eine entscheidende Rolle und sollen anschließend simulativ untersucht werden. In einem weiteren Schritt soll das entwickelte Modul an einer präparativen Chromatographieanlage in Betrieb genommen und auf seine Eignung untersucht werden.

Kontaktperson: Dennis Röcker, d.roecker[ät]tum.de

Link: https://www.epe.ed.tum.de/stt/selektive-trenntechnik/

Kategorien
Abschlussarbeiten Praktika Stellenangebote

Carbon capture & storage: analysis and characterization of biochar production pathways

Short description:
At the Laboratory of Chemical Process Engineering, a new project about carbon capture and storage has recently started. The overall aim of the project is to reduce the amount of carbon in the atmosphere by developing a suitable long-term carbon storage in Bavaria. There are various carbon sources, such as CO2 from air, minerals, organic waste, crops, algae and further sorts of biomass. All of them are carbon-containing resources and, therefore, must be considered as possible feedstock for carbon storage. To achieve a higher carbon content and higher density of these compounds, processes are sought to convert them to long-term carbon storage materials.
Within the scope of this project, biochar as a feasible storage material should be analyzed. Special interest applies to the characterization of different production pathways concerning yield, energy and water consumption and required temperatures for each production pathway. For more details, contact the supervisor.

Description: Good knowledge of German or English language is required, as well as interest in carbon capture and storage techniques. Priorknowledge in any of the following topics is appreciated but not required: LCA, process engineering, reaction kinetics, thermodynamics, and physical chemistry. Good support and training will be provided.

Kontaktperson: Natalie Rosen, natalie.rosen[ät]tum.de

Kategorien
Abschlussarbeiten Praktika Stellenangebote

Immunological diabetes research

Short description:
1. Targeting RORγt/DHODH signaling in islet autoimmunity and Type 1 Diabetes
 2. The role of T cell-specific IL6Rα signaling in maintaining tissue immune homeostasis

Description:
1. We investigate the influence of RORγt/DHODH inhibition on Tregs and different T cell subsets in islet autoimmunity and T1D. Using various in vitro approaches and loss-of-function or T1D mouse models, we dissect the impact on Treg induction and the underlying mechanisms. In collaboration with a biopharmaceutical company, we apply drug candidates targeting these signaling pathways in vivo to different mouse models for T1D to study their effect on autoimmune activation and diabetes progression or prevention.
2. We investigate the crucial role of the high-affinity α-chain of the interleukin 6 receptor (IL6Rα) on CD4+T cells and Foxp3+ Tregs. Using different gain- and loss-of-function mouse models, we dissect the role of the IL6Rα and its complex interplay with other signaling molecules in maintaining Tregs. By that, we investigate how the IL6Rα on T cells contributes to maintaining tissue homeostasis, preventing aberrant immune activation and mediating cross-talk between tissues and immune cells which is important for the function of diabetes-relevant tissues.


Kontaktperson:
Hannah Hipp; Maike Becker – Helmholtz Zentrum München,

Email:
hannah.hipp[ät]helmholtz-muenchen.de

Kategorien
Praktika Stellenangebote

Praktikant (m/w/d) oder erfahrene:r Werkstudent (m/w/d) für den Bereich Anlagentechnik Herstellung

Kurzbeschreibung:
Für unseren Standort Unterschleißheim suchen wir ab sofort zwei Praktikanten (m/w/d) oder zwei erfahrene Werkstudenten (m/w/d) für den Bereich Engineering für mind. 6 Monate. Das Praktikum sollte mind. 3 Monate dauern.

Beschreibung:
Deine Aufgaben:
– Unterstützung vom Team Anlagentechnik bei der Sicherstellung der technischen Anlagenverfügbarkeit bei bspw. Durchführung von technischen Rundgängen
– Durchführen von Membran- und Dichtungsauswertungen und Mitarbeit bei technischen Großwartungen
– Mitarbeit bei technischen Problemlösungen an Anlagen sowie Montagebetreuungen
– Aktualisieren von Messstellenlisten und -analysen
– Support von Optimierungsprojekten und Qualifizierungstätigkeiten
– Zuarbeit bei der Erstellung von Anlagenjahresberichten und der Auswertung der Gruppen-KPIs
– Mitwirkung bei der Erstellung von GMP-konformen Dokumenten sowie Aktualisierung der technischen Dokumentation

Work Experience
Dein Profil:

– Immatrikulation im Studium der Verfahrenstechnik, Pharmatechnik, Lebensmitteltechnologie oder einem vergleichbaren Studium mit Schwerpunkt Engineering
– Offenheit für neue Themen und hohes Engagement
– Sorgfältige und selbständige Arbeitsweise
– Sehr gute Kenntnisse in Deutsch und Englisch

Kontaktperson: Frau Lisa Graf, earlytalent[ät]msd.de

Link: https://jobs.msd.com/gb/en/job/P-100413/Praktikant-m-w-d-oder-erfahrene-r-Werkstudent-m-w-d-f%C3%BCr-den-Bereich-Anlagentechnik-Herstellung

Kategorien
Praktika Stellenangebote

Working Student (m/f/d) – Corporate Venture CapitaI

Kurzbeschreibung: We are looking for interns and working students who want to get to know the VC industry and are interested in deeptech. Students of natural sciences, computer sciences and electrical engineering highly welcome!

Beschreibung: About Fluxunit
Fluxunit is the corporate venture capital fund of the ams OSRAM group. Backed by the world leader in photonics and optical solutions, we invest in innovative products and technologies that have the potential to impact ams OSRAM’s current and future business. We are continuously looking for ambitious entrepreneurs with ground-breaking ideas that want to improve everyone’s daily life with innovative technologies in sensing, illumination, visualization, computation and related fields. We take an active role in our portfolio companies and leverage ams OSRAM’s resources beyond the pure investment to help founders scale up and turn innovative ideas and concepts into commercial success. For the reinforcement of our team we are looking for an entrepreneurial-driven person who is passionate about technology and wants to help us identify successful start-ups and grow our portfolio.

Tasks:
You will support us for 2 days per week for at least 6 months. During this time you will be actively involved in our investment team and get insights into all aspects of the Venture Capital process. You will take over responsibility for own projects and support the investment team in various areas:
-Conduct market and technology analyses and identify attractive technology startups
-Prepare and take part in meetings with CEOs and founders of potential investment targets
-Develop investment hypotheses, financial models as well as exit scenarios
-Assist investment managers in commercial/financial due diligence on potential investments
-Support creating investment memos for the Investment Committee consisting of top executives
-Support the investment team in all aspects of the daily operations of a leading VC fund

What we are looking for:
-Bachelor or Master student with good academic track record, preferably in (Electrical) Engineering, Physics or other Natural Sciences, Computer Science or (Technical) Business Administration
-Entrepreneurial spirit and passion for new, innovative business models, technologies and VC
-Capacity to quickly dive into new technologies, challenge assumptions and develop own hypotheses
-Enjoy working in a dynamic and interdisciplinary team with start-up character
-Structured, independent and responsible way of working
-Strong MS-Office skills
-Fluent in German and English

We offer a competitive salary, the flexibility to align your studies with our schedules and, of course, excellent coffee! 🙂

Next steps:
Please send your CV, certificates and short blurb describing your skills and motivation to our colleague Sebastian

Kontaktperson: Sebastian Stamm, sebastian.stamm@fluxunit.de

Link: https://www.fluxunit.de/

Kategorien
Praktika Stellenangebote

Intern (m/f/d) – Corporate Venture CapitaI Investment Analyst

Kurzbeschreibung: Join our team! If you are passionate about Deep Tech, are studying Engineering, Natural Sciences, Computer Science or Business (with some technology focus) and want to dive into VC, send us a mail. Expect to be an integral part of the investment team with exposure to all aspects of the VC investment process and a steep learning curve!

Beschreibung: About Fluxunit:
Fluxunit is the corporate venture capital fund of the ams OSRAM group. Backed by the world leader in photonics and optical solutions, we invest in innovative products and technologies that have the potential to impact ams OSRAM’s current and future business. We are continuously looking for ambitious entrepreneurs with ground-breaking ideas that want to improve everyone’s daily life with innovative technologies in sensing, illumination, visualization, computation and related fields. We take an active role in our portfolio companies and leverage ams OSRAM’s resources beyond the pure investment to help founders scale up and turn innovative ideas and concepts into commercial success. For the reinforcement of our team we are looking for an entrepreneurial-driven person who is passionate about technology and wants to help us identify successful start-ups and grow our portfolio.

Tasks:
Your fulltime internship will last 3-6 months during which time you will be actively involved in our investment team and get insights into all aspects of the Venture Capital process. You will take over responsibility for own projects and support the investment team in various areas:
-Conduct market and technology analyses and identify attractive technology startups
-Prepare and take part in meetings with founders/ managers of potential investment targets
-Develop investment hypotheses, financial models as well as exit scenarios
-Assist investment managers in commercial/financial due diligence on potential investments
-Support creating investment memos for the Investment Committee consisting of top executives
-Support the investment team in all aspects of the daily operations of a leading VC fund
-Participation in various startup events and conferences

What we are looking for:
-Outstanding academic track record with a Bachelor’s or Master’s degree, preferably in (Electrical) Engineering, Physics or other Natural Sciences, Computer Science or (Technical) Business Administration
-Entrepreneurial spirit and passion for new, innovative business models, technologies and VC
-Capacity to quickly dive into new technologies, challenge assumptions and develop own hypotheses
-Enjoy working in a dynamic and interdisciplinary team with start-up character
-Structured, independent and responsible way of working
-Strong MS-Office skills
-Fluent in German and English

We offer a competitive salary, the flexibility to align your studies with our schedules and, of course, excellent coffee! 🙂

Next steps:
Please send your CV, certificates and short blurb describing your skills and motivation to our colleague Sebastian

Kontaktperson: Sebastian Stamm, sebastian.stamm[ät]fluxunit.de

Link: https://www.fluxunit.de/