Abschlussarbeiten Stellenangebote

Predicting Direct Protein Interactions Using Transfer Learning

Master Thesis at Max Planck Institute of Biochemistry


The Cellular and Molecular Biophysics lab (Prof. Petra Schwille) at the Max Planck Institute of Biochemistry is offering a Master thesis in the fields of Biophysics/Bioinformatics/Data Science. In this highly independent project you will build a Deep Learning model predicting direct physical interactions between proteins. You will combine pre-trained state-of-the-art protein language models with GNNs on graph representations of protein structures and validate and improve the model with explainable AI algorithms. You will be supervised 1:1 by a PhD student and have access to the HPC systems of the Max Planck Society. Ideally you will start in mid-September or early October, but other dates are possible. Previous knowledge in Deep Learning and programming in Python is recommended. Supervision is offered in German or English.


Lab: https://www.biochem.mpg.de/schwille

Supervisor: https://www.biochem.mpg.de/6317372/frohn_bela

Application: bfrohn[ät]biochem.mpg.de