We offer an exciting project at the interface of cell biology and medicine in an international research consortium, teamed up in the SFB 1312. The overarching goal of this collaborative research consortium is to gain a holistic mechanistic understanding of Pancreatic ductal adenocarcinoma, to explain why it resists conventional and targeted therapies and thereby pave the way to novel effective treatments for this devastating disease.
Research Area: Understanding the molecular underpinnings of cellular plasticity in organogenesis, regeneration, and cancer initiation and dissemination. Generation of novel in vitro culture systems (e.g. organoids) from GI cancer patients to determine prognosis, treatment response and resistance mechanisms.
We are looking for a highly motivated master student who is interested in applying biochemical and cell culture methods to identify drivers of the immunosuppressive tumor microenvironment in PDAC and to development specific therapies. We are particularly searching for candidates that have a strong background in protein biochemistry and tumor biology (experience in (confocal) fluorescence microscopy and/or working in cell culture would be advantageous). Please note that this particular project will be a minimum of 6 months, applications for shorter internships (minimum duration: 2 months) will be considered on a case-by case basis.